Products & ReviewLife Sciences
BCL2
Recombinant Human B-cell lymphoma 2 (BCL-2) protein, a key regulator of apoptosis (programmed cell death) and a well-established oncoprotein in many cancers.
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BCL-2 is an anti-apoptotic protein that prevents cell death by inhibiting pro-apoptotic factors like BAX and BAK. Its overexpression is a hallmark of many cancers, contributing to tumor survival and resistance to therapy. Our BCL-2 protein is used for screening small molecule inhibitors (e.g., Venetoclax) and studying apoptosis mechanisms.
Key Features & Benefits:
- Functional Anti-Apoptotic Protein
- Key Target for Cancer Drug Discovery
- Used in Screening for BH3 Mimetics
- High Purity and Stability
Relevant Applications:
- Apoptosis Pathway and Mechanism Studies
- Screening and Characterization of BCL-2 Inhibitors (e.g., Venetoclax)
- Cancer Biology and Drug Resistance Research
- Protein-Protein Interaction Studies within the BCL-2 Family
