![N/A: Proinsulin C-Peptide Analogue Antibody (2D11.H5) [NBP2-44187] - Insulin is a polypeptide hormone produced by cells in the islets of Langerhans in the pancreas. Insulin decreases the levels of glucose in the blood and regulates the metabolism of glucose, fats and proteins. In order to meet the demand for insulin needed by diabetics, the hormone is mass-produced with the aid of genetically engineered bacteria, but can also be taken from pigs and cattle. The diagram to the left illustrates the structure of insulin and proinsulin. Proinsulin is a single polypeptide chain of 86 amino acids that permits correct alignment of three pairs of disulfide bonds. Insulin is derived from proinsulin by cleavage of the C-peptide structure at the dipeptides Arg-Arg and Lys-Arg. Insulin is composed of an A chain of 21 amino acids and a B chain of 30 amino acids, the chains being held together by two disulfide bonds. A third disulfide bond is present within the A chain.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/e0b036e5b9d8ab2c1d4ae5cb6d4feaacfa8e015a-400x275.jpg?w=3840&q=75&fit=clip&auto=format)
Proinsulin C-Peptide Analogue Antibody (2D11.H5)
- Manufacturer
- Novus Biologicals, LLC
- Catalog Number
- NBP2-44187
- Host
- Mouse
- Reactivity
- Caenorhabditis elegans, Human
- Applications
- Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blotting
![Western Blot: Rad17 [p Ser647] Antibody [NB100-56386] - Analysis of Rad17-phos in A) a partial recombinant protein containing phospho Ser647 and B) the same sequence without the phospho serine, and was blocked using the non-phospho control of the immunizing peptide, using this antibody at 1 ug/ml.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/7d853f1b41d1d199c0c1915996275fcb6d43c93f-280x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Western Blot: RALYL Antibody [NBP2-33768] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/dd258223bebb3ca50d413c3466cfc585fef8f04d-164x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Immunocytochemistry/Immunofluorescence: RCN3 Antibody [NBP2-13213] - Staining of human cell line U-2 OS shows positivity in nucleoli.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/7eba33912605c925c372a526de09ed6c0fc41d84-400x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Western Blot: RGS13 Antibody [NBP2-24415] - analysis of RGS13 in 1) transfected 293T cells and 2) untransfected 293T cells using this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/37415f5ce26c35733bd15dbd5482b751465b307f-205x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Western Blot: Rhox10 Antibody [NBP2-23834] - Western blot analysis of Rhox10 Antibody in 12 day mouse testis in the 1) absence and 2) presence of immunizing peptide using Rhox10 Antibody at 1:2000.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/fd64ff409ff2c679fcff1386bd0ca71f40f60958-218x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Western Blot: Rhox13 Antibody [NBP2-24511] - Western blot analysis of Rhox13 in 18 days mouse embryo testis lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24511 at 2 ug/ml.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/47ac187909af206a5648cc82afaf974d1caa7f2c-304x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Western Blot: Rhox9 Antibody [NBP2-23844] - analysis of Rhox-9 in mouse placenta in the 1) absence and 2) presence of immunizing peptide using this antibody. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/69148879661aa8209e3335afae17605ba686d52c-224x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Western Blot: SARS 3b Antibody [NB100-56746] - Analysis of SARS-3b in (A) recombinant fusion protein containing amino acids 31-45 and (B) fusion partner without these amino acids, using this antibody at 0.5 ug/ml.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/2ee2ac07946492dcdabb2ce948b5f574b017df3a-206x400.jpg?w=3840&q=75&fit=clip&auto=format)
![Western Blot: Sars Envelope Protein Antibody [NB100-56562] - analysis of SARS-E in (A) recombinant fusion protein containing amino acids 59-70 and (B) fusion partner without these amino acids, using this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/b87bbd79bb4a8df4c28e0cea93c32aef8841aa69-257x400.jpg?w=3840&q=75&fit=clip&auto=format)