3D cell culture: The technology driving advancement and innovation

Meet the 3D cell culture technology that is breaking boundaries in cancer research, drug discovery, and beyond

12 Apr 2023
Dora Wells
Clinical Content Editor

3D cell culture technology has revolutionized the way researchers study cell behavior and its response to drugs and diseases. By replicating the three-dimensional structure of tissues and organs, 3D cell culture offers a more realistic environment for studying cell behavior, making it a promising tool in drug discovery, disease modeling, and regenerative medicine. In this special feature, we highlight some of the latest advancements in 3D cell culture technology and how they are transforming drug discovery, cancer research, and other fields.

Explore the resources below to learn how AI-based analysis is accelerating translational cancer research, understand how to gain deeper insights with automated culturing and monitoring, explore how to improve your cell assays with a seamless transition to 3D cell models, discover a matrix hydrogel optimized for advanced 3D cell culture applications, and much more.

AI-based analysis: Accelerating translational cancer research

AI-based analysis: Accelerating translational cancer research

3D organoid technology holds potential for many biological research applications. Discover how automated tumoroid analysis in combination with Tecan’s Spark® Cyto live-cell imaging plate reader provides a solution.


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Automated monitoring: Analysis of iPSC-derived 3D cerebral organoids

Automated monitoring: Analysis of iPSC-derived 3D cerebral organoids

Molecular Devices describes a method for semi-automated culturing and monitoring of cerebral organoids, as well as the testing of functional neuronal activity by means of recording Ca2+ oscillations.


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High throughput screening: 5 ways to improve your cell assays

High throughput screening: 5 ways to improve your cell assays

Learn how to empower your cell based research with GrowDex® Hydrogels by UPM Biomedicals. This resource guides you through transitioning from 2D to 3D cell culture to create human-like 3D cell models with scaffold-based matrices.


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Matrix hydrogel: Grow your organoid culture with advanced solutions

New Extragel hydrogel: Grow your organoid culture with advanced solutions

Discover the Extragel Matrix from AMSBIO, a like-for-like replacement for Matrigel™, available immediately with overnight shipping. Extragel is an optimized and effective growth scaffold for organoid, pluripotent stem cell, and advanced 3D culture applications. It’s also suitable for PDX transplantation.


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Expand your 3D cell culture toolkit with these top resources:

  • Find out how organ-on-a-chip (OOC) technology can provide robust and reproducible data that is predictive of the human response.
    Watch video >> 
  • See how the application of advanced cellular imaging capabilities allows all portions of an invading 3D cellular tumoroid structure to be captured in focus.
    Download info >> 
  • Explore how OOC technology is aiding toxicologists in de-risking drug-induced liver injury by providing human-specific safety data.
    Read article >> 
  • Gain tips for reducing microbial contaminations in mammalian cell culture labs, how best to protect cell cultures to enhance cell growth, and more.
    Read article >>
  • Learn about the impact of pH in cell culture and best practices for achieving pH stability.
    Read article >> 

Your recommendations

Find out what researchers across the globe are saying about the products they use! Yuhong Du, at Emory University, shared this review of the ImageXpress Confocal HT.ai High-Content Imaging System by Molecular Devices.


Review of ImageXpress Confocal HT.ai High-Content Imaging System by Molecular Devices
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