ADDA High-Speed Dual Arm Autosampling System

25 May 2011
bridget bridget
Laboratory Director

The ADDA system is a dual-arm, high-speed autosampler that provides ADME discovery scientists with the fastest high-quality sample delivery platform available for LC/MS. At 8 seconds per sample in trap/elute mode, and with 8 unique injection ports, the ADDA system is a comprehensive system designed for the Discovery lab.

With the ADDA system, permeability, transport, metabolic stability and drug-drug interaction screening assays can be rapidly turned around with a single mass spectrometer system, saving critical time in the drug discovery process.

The system achieves its speed and flexibility with 2 high-speed, high-accuracy robotic arms, each equipped with a syringe and four injection ports. Batches can be submitted to use either one arm or both arms simultaneously. The plumbing can be set up on a per-injection-port basis, allowing up to 8 different gradients and columns to be left on the system. Four onboard valves simplify the plumbing for the system. Testing with multiple chromatographic setups, direct infusion and high-speed trap and elute experiments can be performed in a completely automated fashion. The ADDA system represents a significant leap forward in both speed and cost savings within high throughput drug discovery.

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