Adocia Announces Preliminary Positive Clinical Results for Its Combination of Long-Acting Insulin Glargine and Fast-Acting Insulin Analog Lispro, Biochaperone® Combo

Adocia has announced positive preliminary results for the first clinical trial on an innovative formulation combining insulin analog Glargine (Lantus(R), Sanofi), the gold standard basal insulin, with a rapid-acting insulin analog, Lispro (Humalog®, Eli Lilly) using Adocia's BioChaperone® technology.

BioChaperone technology enables the solubilization of insulin Glargine at physiological pH, which enables its combination with prandial insulins analogs such as insulin Lispro in solution. Eight patent applications have been filed to protect this innovation until 2032.

The objective of this trial was to show that this combination of the most widely used basal insulin (Lantus) and one of the best commercial prandial insulins (Humalog) formulated with the BioChaperone technology has the potential to help patients improve their blood glucose control more effectively than with a Premix formulation of insulin analog (Humalog Mix®, Lispro and Protamine).