Advances in HPLC/UHPLC Technology & Method Development Webinar Series

In this series of free webinars, explore the latest advances in HPLC/UHPLC technology and method development. Discover the new techniques and technologies helping researchers simplify the analysis of polar compounds, automate process monitoring in pharmaceutical and biopharmaceutical production, optimize oligonucleotide analysis, and much more.

Register by clicking on the live events below to hear from analytical science and separations experts. Ask the speakers your questions in the live Q&A sessions following each presentation. Plus, check out a selection of our on-demand webinars and download related resources to supplement your own research.

Automated process monitoring via liquid chromatography (LC)

Monday, August 16, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

In this webinar, Dr. Daniel Kutscher, from Agilent Technologies, will present a newly developed online LC platform, which provides automated sample analysis via direct injections or retained samples from flow reactors, batch reactors, upstream bioreactors, and downstream purification devices.

Easy, rapid and direct analysis of challenging polar compounds

Wednesday, August 18, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Connor Flannery, from Restek, will introduce a simpler approach to the retention and separation of these challenging compounds — a unique stationary phase specifically designed to selectively retain polar analytes. Flannery will highlight specific application examples that will illustrate the rapid and direct analysis of underivatized amino acids, ultrashort-chain PFASs, glyphosate, and other polar contaminants.

LC/MS to reveal the hidden post-translational modifications in neurodegeneration

Available to view on demand

Dr. Blaine Roberts, from Emory University, discusses the application of quantitative proteomics to a large set (~2,000 samples) of cerebral spinal fluid (CSF) samples to better understand the role of acute-phase proteins in Alzheimer’s disease. Roberts will also talk through a rapid 10-minute triple quad mass spectrometer method with heavy-labeled peptides that can provide in-depth information about the amount of targeted proteins in human CSF. Register to discover how the implementation of quantitative mass spectrometry and ion mobility reveal hidden biology and improve our understanding of a complex disease.

The power of (U)HPLC selectivity for diverse pharmaceutical methods

Available to view on demand

With so much attention paid over the years to column efficiency, it is important not to forget about the power of selectivity. In this webinar, Dr. Jason Anspach will cover the basics of chromatographic selectivity and provide you with a template to help you decide between fully porous or core-shell particles to get the most out of your pharmaceutical separations.

Optimize IP-RP method development for oligonucleotide analysis

Available to view on demand

Ensuring high-quality oligonucleotides for therapeutic applications relies on robust analytical methods. In this webinar, hear from principal scientist Dr. Brook Koshel as she discusses method development considerations when selecting an appropriate ion-pairing agent. She also shares tips and tricks for developing efficient methods for ion-pair reversed-phase (IP-RP) analysis of oligonucleotides.

Improving the sensitivity of LC-MS methods for characterization and quantitation of synthetic oligonucleotides

Available to view on demand

Join Brian Rivera, from Phenomenex, as he discusses how LC-MS sensitivity can be increased by mobile phase optimization and column selection. He also demonstrates how to minimize adduct formation and enhance ionization efficiency, which can in turn increase MS sensitivity for improved characterization and quantitation data.

Oh no! Not another boring webinar on column lifetime?

Available to view on demand

Are you looking for a comprehensive summary on how to protect your HPLC column from early failure, clogging and performance loss? Join Andreas Borowiak, from Agilent Technologies, to learn what the typical lifetime for an HPLC column should be, how to identify the root cause of early column failure, how to protect your column from solvent contaminations, and how to properly clean and store your HPLC columns.

Discover more free resources here:

• Advances in HPLC Special Feature: Learn about the latest HPLC systems, read interviews with leading scientists and download new resources to support your method development. Visit special feature >>
• How to Buy HPLC Technology: In this free HPLC buying guide, discover the key factors and application considerations when looking to buy new columns. Plus, read impartial reviews to gain insights from industry-leading professionals. Download eBook >>
• How to Buy LC-MS Technology for Life Sciences: In this free LC-MS buying guide, discover the key factors and application considerations when looking to buy LC-MS technology, from sample prep to the latest LC-MS system. Plus, read impartial reviews to gain insights from your peers around the world. Download eBook >>
• Analysis of pesticides in cannabis products: In this video on The Scientists' Channel, Dr. Nathaly Reyes Garcés explains a simple workflow for the accurate analysis of pesticides in cannabis products via solvent extraction and GC analysis. Colton Myers discusses his work analyzing terpenes in cannabis through headspace analysis, and Ashlee Gerardi outlines the focus for Restek and how its team can help with bespoke cannabis testing workflows and method development, in the face of ongoing changes within the industry. Watch here>>
• Liquid chromatography - Tips, tricks & guidance: In this eBook, we look at Agilent Technologies’ products portfolio to help you navigate the increasingly complex landscape of LC. Discover how transformative Agilent’s InfinityLab LC/MSDiQ and Poroshell 120 columns could be to your LC workflow. Download eBook >>

Register for the Advances in HPLC/UHPLC Technology & Method Development Webinar Series here>>