Agencourt^® RNAdvance™ Tissue System Delivers Higher Yields For Gene Expression Studies

Beckman Coulter introduces the Agencourt RNAdvance Tissue system for isolation of total RNA from mammalian samples.

The Agencourt RNAdvance Tissue process is based on the patented Agencourt SPRI^® (Solid Phase Reversible Immobilization) paramagnetic bead nucleic acid purification technology. The new system produces clean RNA with high recovery, in single-tube or 96-well formats, while eliminating organic solvents, vacuum filtration and centrifugation steps. The simple Agencourt RNAdvance Tissue procedure enables higher recovery of total RNA than traditional column-based approaches. This allows researchers to maximize the use of precious tissue samples without compromising RNA integrity.

The Agencourt RNAdvance Tissue process can be automated on the Beckman Coulter Biomek^® NX liquid handling workstation for a fully validated and supported walk-away solution. For microarray applications, the Agencourt RNAdvance Tissue system can be used with the Agencourt RNAClean^® technology for a complete solution for superior RNA purity and recovery.

“The ability to extract and purify high quality RNA from multiple tissue samples simultaneously will greatly facilitate studies that correlate gene expression signatures to disease or drug toxicity,” commented Erik Gustafson, Ph.D., Director of Research and Development for Agencourt. “This flexible, scalable system enables our gene expression customers to extract and purify RNA from up to 96 tissue samples, which is ideal for parallel sample processing applications.”

The Agencourt RNAdvance Tissue system augments the comprehensive Agencourt product line of advanced, easy-to-use solutions for RNA isolation and purification from tissues, cells and in vitro reactions.