Analysis of tyrosine kinase signaling in human cancer by stable isotope labeling with heavy amino acids in mouse xenografts utilizing Mouse Express Lysine 13C6 Mouse Feed

Tyrosine kinases (TK) play important roles in the induction of cell growth, survival and migration. In this application note, Cambridge Isotope Laboratories presents a novel proteomic approach to label tumors in nude mice xenografted with human cancer cells using Mouse Express^® L-Lysine (13C6, 99%) Mouse Feed (MF-LYS-C).