ResourceDrug Discovery & Development
Assessing mRNA capping efficiency and Poly(A) tail length with simple electrophoretic separation
15 Apr 2025Manufacturing high-quality mRNA and performing comprehensive quality control prior to applications is essential for mRNAbased technologies. The USP has issued draft guidelines for accurate analysis of 5′ capping efficiency and 3′ poly(A) tail length to highlight consistency in products.
Explore kits that allow for assessment of these mRNA quality attributes using quick and straightforward electrophoretic separation formats. Circumventing the expense and limitations associated with more complex technologies, these CELLSCRIPT kits enable scientists to obtain reliable, same-day results.