Beckman Coulter Life Sciences accelerates high-throughput genomic sample preparation

New Biomek Echo One System reduces workflow time from hours to minutes

2 Jul 2024
 Biomek Echo One System

The new Biomek Echo One System from Beckman Coulter Life Sciences

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, accelerates high-throughput genomic sample preparation workflows to deliver results faster with the launch of its Biomek Echo One System. The new solution provides versatile integrated acoustic liquid handling options for applications in genomic workflows, including high-throughput isothermal DNA assemblies and NGS library sample preparations.

The Biomek Echo One System combines two Beckman Coulter Life Sciences core liquid handling instruments: the Echo 525 Acoustic Liquid Handler and the Biomek i7 Hybrid Workstation, which can be integrated with existing laboratory automation instrumentation. The new platform can execute library preparation steps such as extraction, fragmentation, ligation, normalization and pooling along with requisite actions such as centrifugation, shaking and thermal incubation in one automated method.

Laboratories are now empowered to achieve ultimate workflow flexibility, from standalone PCR reaction setups to a fully executed NGS library preparation protocol using all of the integrated devices. The intuitive system requires minimal user training to ensure laboratory staff can unleash the benefits immediately. Users can easily scale up walk-away time and throughput to adapt to changes in workflow demands and needs, creating a future-proof solution that can grow with laboratory needs and complexities.

The Echo 525 Acoustic Liquid Handler uses sound energy to move precise, nanoliter-scale droplets in a combinatorial fashion that significantly exceeds traditional sample transfer speeds for workflows such as DNA assembly, including pooling and normalization steps. Using traditional liquid handlers, laboratories have reported eight-hour workflows slashed to just 30 minutes when performed on an Echo 525 liquid handler with seamless pass-offs to the Biomek Workstation for further downstream execution of the workflow.

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