Berthold Technologies Presents the Second Generation Multimode Microplate Reader Mithras at analytica 2014

17 Mar 2014

Lois Manton-O'Byrne

Executive Editor

Berthold Technologies presents the second generation of its Multimode Microplate Reader Mithras, the Mithras² LB943 with monochromator and filter technology.

The Mithras²LB943 works with the flowing reading technologies:

UV/VIS Absorbance
Fluorescence and FRET
Fluorescence Polarisation
Time-Resolved Fluorescence (TRF and TR-FRET)
Luminescence
BRET and BRET²
AlphaScreen^® and AlphaLISA^®

Already implemented in the TriStar² the patent-pending optical concept ONE-4-ALL is employed for sensitive luminescence, fluorescence and absorbance measurements – with performances as in dedicated instruments – in the Mithras² for filter-based reading. Additionally the instrument is equipped with two double monochromators with high blocking efficiency and high f-number (increased transmission) for filter-less measurements of absorbance and fluorescence. For utmost sensitivity in luminescence a third specially selected and extremely noise-reduced detector is engaged in the HiSens position which is used for Alpha and BRET readings, too.

In addition, the multimode reader TriStar² capable of these reading technologies include;

absorbance
fluorescence
FRET
luminescence
BRET and BRET²

TriStar² with multiple measurement technologies employs the new patent pending optical concept ALL-4-ONE, for the first time enabling luminescence, fluorescence and absorbance measurements with highest respective sensitivity as known from dedicated instruments. In comparison to its predecessor the optics has been further improved and an improvement in detection limits in fluorescence has been achieved.

The third featured product is the NightSHADE in vivo plant imager. For applications such as monitoring gene expression and circadian rhythm with reporter genes e.g. GFP or luciferase, observation of plant growth, examination of stress tolerance, measuring of delayed fluorescence, bio-photon imaging and drug screening the NightSHADE offers unique features for plant research.