Bio-Rad’s Newest NGC™ Chromatography Systems Automate Workflow

Bio-Rad Laboratories, Inc. has announced the launch of two new NGC Medium-Pressure Chromatography Systems, the NGC Discover™ and NGC™ Discover Pro Systems. The automation capabilities of both systems make them ideal for advanced purification applications such as method optimization and multi-step and tandem protein purification.

Bio-Rad optimized the Discover and Discover Pro Systems for pharmaceutical environments. These systems are available with a 10 ml/min pump module or with the recently released NGC 100 ml/min pump module, which enables flow rates up to 200 ml/min when used in combination with a buffer blending module. The Discover Systems further increase throughput by being able to load multiple samples and run up to 15 columns sequentially. In addition, the Discover Pro System can collect 12 large-volume fractions via its outlet valve. These higher flow rates and throughput capabilities — all under software control for maximum automation — will enable pharmaceutical researchers to maximize efficiency and productivity in the lab.

The Discover Systems’ best feature, however, may be their ease of use, a hallmark of the NGC family of chromatography instruments.

“Over the past 18 months, researchers have embraced NGC Systems due to their straightforward operation that allows even chromatography novices to get up to speed in only one or two runs,” said Kamni Vijay, Bio-Rad marketing director, Protein Function Division, Life Science Group. “By reimagining chromatography instrumentation from the ground up, we’ve created a system that’s an asset in making important scientific discoveries.”

All NGC Systems feature the same modular design with interchangeable plug-and-play modules that allow researchers to scale the system according to their throughput needs.

Other benefits of the NGC Chromatography System family include:
• Faster setup — the Point-to-Plumb™ feature offers step-by-step LED-guided plumbing of the system and quicker instrument setup
• Automated methods and analysis — ChromLab™ Software provides method templates that meet any purification need and it reduces tedious analysis with time-saving features such as single-click peak integration and the ability to stack and overlay chromatograms
• Robust performance and regulatory compliance — all systems can be operated in compliance with 21CFR Part 11 regulations using ChromLab Software Security Edition. System-level IQ/OQ validation and rigorous testing ensure that all systems live up to the high-throughput demands of a pharmaceutical environment