Biotage Introduces Unique, Entry-Level System for Microwave-Assisted Peptide Synthesis

Biotage® introduced the Initiator Peptide Workstation for manual microwave-assisted peptide synthesis. The Workstation utilizes a unique microwave peptide vial available in two sizes; 2-5 mL for 75-150 μmol scale or 10-20 mL for 250-500 μmol scale synthesis.

The Initiator Peptide Workstation enables simple workflow for microwave-assisted peptide synthesis in a Biotage Initiator microwave synthesizer without system modifications. Synthesis is performed directly in the specially designed microwave vial, then filtered and washed using the wash station. Material can be collected in a standard GL 45 laboratory glass bottle, 50 mL centrifuge tube or even a round bottom flask.

A versatile solution for both microwave assisted solution and solid phase peptide synthesis

It is also cost-effective system, delivering a high level of control for close monitoring of the quantity of reagents used, resulting in minimized waste and reduced cost.

The Workstation is a simple solution for performing various types of chemistry using microwave irradiation under atmospheric conditions at temperatures up to 100°C including: solution and solid phase synthesis, organic, peptide (Fmoc and Boc), peptoid and PNA (peptide nucleic acid) synthesis. The Initiator Peptide Workstation was developed to address the needs of peptide chemists and organic chemists synthesizing peptides and peptidomimetics, including difficult post-synthetic modification of sequences using microwave irradiation.

“At Biotage, we are committed to developing the tools needed by the global peptide community” says Amit Mehrotra - Product Manager, Peptide Chemistry “our collaboration with key researchers has clearly identified the need for an entry-level system for microwave-assisted peptide synthesis. The Initiator Peptide Workstation illustrates our continued commitment to this important area of science.”
For more information regarding Biotage peptide synthesis and purification products, please visit the company article page.