Biotage to Showcase Unique Sample Preparation Tools at PITTCON 2009

Biotage, a leading supplier of tools and technology for medicinal and analytical chemistry, announces the showcasing of two products that are easy to use, offer minimal method development time, and are highly cost-effective for the removal of phospholipids, salts and proteins in bioanalytical samples. ISOLUTE® SLE+ and EVOLUTE® will be showcased exclusively at booth #3673 at PITTCON 2009, McCormick Place, Chicago from 8-13 March 2009.

ISOLUTE SLE+ Supported Liquid Extraction plates, are rapidly replacing traditional protein precipitation, liquid-liquid extraction and solid phase extraction protocols because chemists are able to develop methods quickly with excellent analyte recovery and well-to-well reproducibility. Problems such as emulsion formulation and automated pipetting of liquid layers are also avoided, as the two phases do not come into direct contact. The ISOLUTE SLE+ mechanism is extremely robust and eliminates all off-line steps, cutting sample preparation time in half.

Also on view at PITTCON will be the EVOLUTE® series of sample preparation products for the simple and fast removal of phospholipids, salts and proteins in bioanalytical samples. These high performance products allow scientists to use a generic approach for a wide range of compounds, thereby reducing method development time while producing super clean extracts.

EVOLUTE ABN is an advanced water-wettable polymer-based sorbent that extracts acidic, basic and neutral analytes from biological fluids and other aqueous matrices. Developed specifically for analyte quantification by LC-MS/MS, EVOLUTE ABN’s optimized pore structure minimizes the retention of high molecular weight endogenous materials present in complex sample matrices.

EVOLUTE CX is a mixed-mode resin-based SPE sorbent that extracts a wide range of basic drugs from biological fluid samples. EVOLUTE CX removes matrix components such as proteins, salts, non-ionizable interferences and phospholipids, delivering cleaner extracts with reproducible recoveries for accurate quantitation.