BMG LABTECHS´s PHERAstar Plus sets new standards in HTRF^® , luminescence and fluorescence polarization reading

To satisfy the ever-increasing demands of the HTS community a new version of the highly successful microplate reader PHERAstar is available from BMG LABTECH, the PHERAstar Plus. The PHERAstar Plus features Advanced HTRF^® / TR-FRET, Advanced Luminescence, and Advanced Fluorescence Polarization reading modes by integrating the latest technological advancements in optics and electronics. Coupled with the new powerful data analysis software package MARS, these new features extend the application versatility of the PHERAstar Plus.

The PHERAstar Plus is a simultaneous dual emission HTS microplate reader offering all leading detection technologies including fluorescence intensity / FRET, fluorescence polarization, time-resolved fluorescence / TR-FRET, laser-based AlphaScreen^®, luminescence / BRET, and UV/Vis absorbance. The new instrument provides both enhanced HTRF^® performance with market leading Z’ and TR-FRET ratio performance and a fourfold increase in luminescence sensitivity. This is made possible by BMG LABTECH’s innovations in the modular optical system combined with the unique well-proven detection technology. The PHERAstar Plus is the only microplate reader on the market with five photomultiplier tubes (PMTs) and Simultaneous Dual Emission (SDE) technology optimized for specific reading modes and the capability to capture TR-FRET decay curves in real-time for assay optimization.

The PHERAstar Plus will be delivered with a new version of BMG LABTECH’s established Reader Control and a completely new MARS Data Analysis Software with significant ease-of-use enhancements such as S/N, Z’, and many other standard calculations. The Wizard creates an easy step-by-step calculation of a standard curve and the Template Manager is an excellent tool for building complex data processing protocols. Thus, user-defined data analysis is done simply with one click of the mouse. Improved robotic integration capabilities, digital signature and the 21 CFR part 11 compliance of MARS complete this new software.