Bruker and IPT launch SampleStream–timsOmni integration for automated proteoform profiling

21 Nov 2025
IPT SampleStream™ integrated into a Bruker Elute HT coupled to the timsOmni™

IPT SampleStream™ integrated into a Bruker Elute HT coupled to the timsOmni™

Bruker and Integrated Protein Technologies, Inc. have announced a joint initiative to combine SampleStream™ with timsOmni™ for automated, high-throughput proteoform profiling.

The SampleStream™ technology from IPT enables and streamlines the analysis of proteoforms by mass spectrometry, delivering exceptional sample recovery and efficient cleanup. The combination of MSn enrichment on the timsOmni™ with the SampleStream™ technology is uniquely suited for high-throughput proteoform analysis.

Dr. Philip Compton, CEO at Integrated Protein Technologies, Inc., said, “Together, we see significant opportunity to bring high-throughput, intact and top-down protein analysis to a broader global market. Integrating SampleStream with Bruker’s recently released timsOmni system represents a powerful combination that could accelerate innovation and adoption of these data types across proteomics, biopharma, and clinical research.”

Daniel Hornburg, Vice President, Biomarkers & Precision Medicine, Bruker, commented, “Proteomics is evolving rapidly beyond canonical protein maps. With Bruker’s innovations, we’re pushing the boundaries of bottom-up analysis for example for PTMs and cancer neoantigens, and at the same time, making proteoform profiling more efficient, accessible and confident. By closing the gap between these worlds, we’re giving scientists the tools to see biology as it truly operates and study health and disease.”

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