Caliper Life Sciences Launch IVIS Spectrum CT

Caliper Life Sciences, Inc. announces today the availability of the IVIS Spectrum CT, a breakthrough preclinical imaging system. The new system integrates advanced optical imaging with low dose microCT (micro computed tomography), enabling simultaneous molecular and anatomical longitudinal studies. Researchers are provided with vital and unparalleled insights into complex biological systems in small animal models used to develop new, clinically translatable discoveries.

A broad array of applications exist for the new instrument, with musculoskeletal, vascular, oncology, phenotyping, cardiovascular and respiratory disease among those areas particularly enabled by the integration of optical and microCT imaging.

The Spectrum CT expands upon the versatility and advanced optical features of the Caliper IVIS and Maestro platforms, the leading preclinical optical imaging technologies with over 1250 instruments placed worldwide. The system offers powerful, flexible and exquisitely sensitive optical molecular imaging integrated with complementary, ultra-fast, low-dose microCT anatomical imaging. Features include optical sensitivity capable of achieving detection of a few cells and 3-dimensional reconstructions of optical molecular bioluminescence and fluorescence signals, integrated with 3-dimensional anatomical microCT images. Designed for high-throughput, quantitative, non-invasive longitudinal analysis of large cohorts of animals, Spectrum CT enables new, clinically translatable insights.

Regarding one example application, Lloyd Miller, MD., PhD., Assistant Professor at UCLA Departments of Medicine and Orthopaedic Surgery commented, “The Spectrum CT provided extraordinary 3-dimensional images of bacteria and infection-induced inflammation in implant biofilms and the anatomical interactions between bone and the implant. This is achieved noninvasively in the same mice and in real-time. The instrument represents a major advance in the field of in vivo imaging and we are excited about the opportunity to use the Spectrum CT for our research.”