Cellular Origins and 3P innovation collaborate to accelerate industrialisation of CGT manufacturing

Cellular Origins, a TTP company, focused on enabling scalable, cost-effective, and efficient manufacture of cell and gene therapies (CGTs), has announced a collaboration with 3P innovation, a leading engineering company and supplier of automated fill-finish equipment. The partnership will integrate 3P innovation’s cryoFIL™ cryovial filling platform within Cellular Origins’ robotic system, Constellation™, expanding the system’s capabilities by enabling automated filling of cryovials within a closed and sterile environment.

3P innovation’s cryoFIL platform is designed to automate and streamline filling processes in cell and gene therapy workflows, incorporating the company’s technology within a cGMP compliant robotic platform. Designed to provide reliable and repeatable liquid filling, cryoFIL’s automated workflow utilises a closed loop filling and 100% weight verification approach to ensure the maximum yield of manufactured therapies.

The collaborative partnership will undertake the physical and digital integration of cryoFIL within Constellation, centring around the development of a system for seamless robotic docking with cryoFIL. The integration will allow manufacturing processes that require interfacing with vials and other open format containers to be fully automated, maximizing production efficiencies.

Further expanding Constellation's system’s capabilities, the integration of cryoFIL will enable users to alleviate the requirement for manual and problematic process steps in CGT manufacturing that can require significant time and labour investment.

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