Cerno Bioscience Extends Award-Winning MassWorks™ Software for Formula ID on High Resolution and Ion Trap Mass Spectrometers

23 Oct 2007
Greg Smith
Analyst / Analytical Chemist

Cerno Bioscience announces the launch of MassWorks™ sCLIPS (Self Calibrated Lineshape Isotope Profile Search), the latest addition to the MassWorks mass spectrometry software suite. Using Cerno’s patented calibration techniques, users of High Mass Accuracy (HMA) instruments can now dramatically improve the results of formula identification and easily obtain higher quality, reproducible data through accurate line-shape calibration. For the first time, sCLIPS now also enables ion trap users to obtain quality formula identification of unknown formula. MassWorks was originally launched in 2006, and received the prestigious Editors’ Choice Bronze Award at PITTCON 2006. MassWorks is an easy-to-use post acquisition software system using Cerno’s patented MSIntegrity calibration technology to work directly with data from a wide range of mass spectrometers.

High resolution mass spectrometry instruments often cannot provide a unique formula ID match when using mass accuracy alone. New MassWorks sCLIPS enables users of HMA instruments including TOF, high resolution quadrupoles, Orbitrap, magnetic sector, and FTMS to easily enhance formula ID accuracy without the need to run calibration standards. Cerno’s patented technology provides a calibrant-free method for significantly improving accurate-mass-only formula searches.

MassWorks sCLIPS also has significant benefits for users of ion trap spectrometers. Although these instruments are extremely powerful and sensitive, they typically cannot provide accurate formula confirmation or identification of individual ion peaks. sCLIPS uniquely enables formula ID through high spectral accuracy when running ion traps in zoom and enhanced resolution modes by virtue of its patented line shape calibration method.

“Users of single and triple quadrupole instruments have already seen dramatic improvements when using MassWorks CLIPS, and with new MassWorks sCLIPS Cerno can offer considerable benefits to scientists performing formula ID on High Mass Accuracy and ion trap mass spectrometers.” comments Dr. Yongdong Wang, president of Cerno Bioscience.

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