Comprehensive high-resolution targeted LC-MS/MS analysis of challenging signalling lipids

LC-MS has been the standard choice for the analysis of signalling lipids, but the method poses specific challenges, such as peak tailing and loss of recovery for phosphate groups containing lipids. Explore an optimized LC-MS/MS method from YMC Europe that covers 388 signalling lipids from 17 lipid classes. Discover how the bioinert coated YMC Accura Triart C18 column combines high resolution with high sensitivity for phosphate groups containing lipids.