Corning Introduces New Nanofiber Cell Culture Products

Corning Life Sciences has introduced four new products featuring the Ultra-Web™ synthetic surface technology. This breakthrough 3-D nanofiber technology is being applied to two of Corning's 96-well microplates and two 100mm tissue-culture dishes. Customers will now have access to products that mimic in vivo cell growth conditions, leading to improved outcomes in cell culture, cell-based bioassays and other in vitro-related applications.

Ultra-Web synthetic surfaces create a culturing substrate that resembles structural components within the basement membrane or extracellular matrix and offer cells in vivo-like fibrillar topographies that, unlike biological coatings, are more stable, more consistent from lot to lot and animal component free. This technology also enables more reproducible and biologically meaningful results in an easy-to-use, cost-effective and time-efficient manner for cell research and cell-related applications.

Ultra-Web Synthetic Surface Applications:

• Ideal for culturing liver, neuronal, kidney and stem cell lines or primary cultures where current surfaces do not provide the necessary culture performance or function
• Replacement for poly-lysine or animal-derived biological coatings
• Ideal substrate for binding cell attachment and growth factors to create more in vivo-like culture environments
• Compatible with cell-based luminescence-reporter gene and FLIPR calcium flux assays
• Promotes more in vivo-like morphology (spheroid and dome formation)

Ultra-Web™ Synthetic Surfaces are available with two surface chemistries:

• Untreated electrospun polyamide nanofibers with a slightly hydrophilic surface
• A positively charged hydrophilic polyamine surface for enhanced cell attachment or the ability to covalently attach biomolecules