Custom Phospho-Specific Polyclonal Antibodies

20 May 2009
Emily Marquez-Vega
Publishing / Media

Milligram quantities of highly purified Phospho-specific polyclonal antibodies are available from AMSBIO custom designed for optimal recognition of specific phosphorylation sites on the protein of interest to research scientists.

Phosphorylation events are integral to cellular regulation functions including activation of enzymes and receptors, cellular transcription, signal transduction and cell signaling networks. Custom phospho-specific antibody production can ensure that the peptide mimics the natural conformation and activity found in the protein. Phosphorylation often results in functional changes in the activity of a protein, and having antibodies recognising the phosphorylated state (as well as the corresponding non-phosphorylated state) can be integral for studying protein pathways.

Drawing upon many years experience AMSBIO has developed a custom phospho-specific antibody production service that is both reliable and produces high quality product. Following peptide synthesis, conjugation, immunisation and anti-sera production all antibodies are purified using a double column immuno-affinity method. The purified phospho-specific antibody is then fully characterised using both dot-blot and ELISA techniques.

Further information on AMSBIO custom phospho-specific polyclonal antibodies may be downloaded by following the company article webpage link on the right hand side of the screen.

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