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Free Webinar - Enhancing the Mass Spectrometry Characterization of Antibody Drug Conjugates (ADCs)
14 Sept 2016Alex Waite
Editorial Assistant
Antibody-drug conjugates (ADCs) are monoclonal antibodies chemically linked to biologically active small molecule drugs. ADCs form a new class of biotherapeutics that represent a rapidly growing portion of the drug discovery pipeline in pharmaceutical companies.
In this free webinar from SelectScience® Mike Peddicord, Senior Research Scientist at Bristol-Myers Squibb, will discuss how intact mass LC-MS data is used to determine drug-to-antibody (DAR) ratios, and some ways that this information can be used to drive decisions in the development of ADCs.
Key Learning Objectives:
- A look back at some older methods of determining the DAR value from an LC-MS data set, and how these methods were time-consuming, and not always user-friendly
- Why the Agilent DAR calculator is a great software tool to enhance the speed of data processing and data reporting for LC-MS intact mass measurements of ADCs