FUJIFILM Irvine Scientific expands BalanCD CHO media platform portfolio for bioprocessing

Chemically defined media optimized for growth and productivity of CHO cells in perfusion and batch and fed-batch bioprocesses

11 Apr 2023
James Li
Blood Banking Scientist

FUJIFILM Irvine Scientific, Inc has launched the expansion of its BalanCD CHO Media Platform portfolio with the addition of two new, chemically defined growth media: BalanCD CHO Perfusion and BalanCD CHO DG44. The BalanCD CHO media portfolio is designed to ensure maximized growth, viability, and productivity of Chinese Hamster Ovary (CHO) cell lines via a scalable platform for reliable production and seamless workflow through all stages of development and manufacture, from small-scale shake flasks to large bioreactors. These new additions extend the platform with specific media designed to support DG44 cell lines and perfusion culture platforms for the commercialization of monoclonal antibodies, recombinant proteins, biosimilars, and other biomolecule-based biotherapeutics.

BalanCD CHO Perfusion medium is a chemically defined, animal component-free medium optimized to deliver robust cell growth and productivity in steady-state, perfusion CHO culture. The medium is verified to meet industry performance standards for perfusion culture conditions including: volumetric productivity (VP); cell specific perfusion rates (CSPR); and vessel volumes per day (VVD). BalanCD CHO Perfusion is a complete and ready-to-use medium that is adaptable and scalable for a variety of perfusion culture platforms, including perfusion mimic and perfusion-capable bioreactors.

Erik Vaessen, chief business officer, FUJIFILM Irvine Scientific, said: “With CHO cells being such a pivotal part of many biotherapeutic development and manufacture pipelines, FUJIFILM Irvine Scientific designed the BalanCD CHO platform to deliver consistent, high-quality growth of CHO cells and production of biomolecules to accelerate the development and manufacture of life-saving therapies for patients around the world and achieve more cost-efficiences within biotherapeutic manufacturing.”

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