Live Cell Dispensing Without Edge Effects

20 May 2007

KD Scientific’s UltraSpense 2000 eliminates edge effects and delivers more viable cells more uniformly to 384 well microplates when compared to conventional peristaltic dispensers.

UltraSpense 2000 eliminates edge effects and fluid drops sticking to the dispensing tips when dispensing live cells. The net result is that the accuracy of seeding is much improved with the use of the UltraSpense, leading to more reliable results.

As a result, more of the wells are usable for assays making productivity and throughput increase dramatically. By simply recovering the perimeter row of a 384 well plate, a 25% gain in usable assays is achieved with CHO, Hek293 and Cos-7 cells.

UltraSpense 2000 solves many problems experienced with peristaltic dispensers with a specially designed coated manifold that uniformly distributes material to all 8 tips. This is combined with a proprietary pumping algorithm that overcomes the natural tendency for fluids to accumulate on the outside of the manifold tips.

In addition, without the potential for uneven tubing wear associated with peristaltic rollers, the UltraSpense 2000 maintains its consistent performance after millions of dispense cycle.

These new technologies deliver inherently greater accuracy and consistent volumes across a wide range of viscosities with high reliability. The improved technology is simple to use and saves in operating and maintenance costs.

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