Mag-Trypsin (Magnetic Immobilized Trypsin)

Clontech’s new Mag-Trypsin (TPCK-trypsin immobilized on magnetic beads) allows trypsin to easily be removed from a protein digestion mixture using a magnetic separator after the reaction is complete.

TPCK treatment prior to immobilization inhibits chymotrypsin activity without any effect on trypsin. Unlike agarose-linked immobilized trypsin, Mag-Trypsin does not require any centrifugation or use of columns. It provides a simple method for eliminating trypsin contamination after digesting protein samples to their peptide constituents in preparation for such techniques as mass spectroscopy or peptide enrichment.