Mechanistic Toxicology Solutions from CXR at SOT 2011

Visit CXR Biosciences to learn more about combining innovative and standard mechanism-based approaches to improve compound development or resolve unexpected toxicity issues. The portfolio also includes in vitro & in vivo toxicity biomarkers, screening & investigative toxicology services and novel transgenic animal models (humanized transADMET mice).

CXR Biosciences will work with you in a flexible, consultative and advisory manner to design and interpret state of the art investigative safety studies that deliver the results you need, whilst reducing time, cost and use of animals.

Meet the team; Drs. Cliff Elcombe, Audrey Vardy, Simon Plummer and Jillian McEwan at;

Booth # 1609 at ToxExpo.

Or visit our posters;

Poster #327) THE EFFECTS OF TRIS (2-ETHYLHEXYL) TRIMELLITATE (TOTM) ON GENE EXPRESSION ASSOCIATED WITH TESTICULAR MAL-DEVELOPMENT (TMD) IN RAT FOETAL TESTES
Elcombe, Clifford R1; Dhritiman, Dan1; Farrar, David G2 and Plummer, Simon M1. CXR Biosciences Ltd, Dundee, Scotland, UK1 and INEOS Chlor Limited, Runcorn, UK 2 (Abstract #1048).

Poster #320) IMMUNOHISTOCHEMICAL AND CHIP MICROARRAY ANALYSIS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA (PPAR) IN FETAL RAT TESTES EXPOSED IN UTERO TO DIBUTYLPHTHALATE
Plummer, Simon M1; Dan, Dhritiman1; Quinney, Joanne C1; Millar, Michael3; Hallmark, Nina2; Phillips, Richard D2; Elcombe, Clifford R.1. CXR Biosciences, Dundee, Scotland, UK1, ExxonMobil Petroleum & Chemical, Hermeslaan, Belgium2 and MRC Human Reproductive Sciences Unit, Edinburgh, Scotland, UK (Abstract #1041).