Meet the new Crystal16: The new industry standard

14 Jun 2022
Lee Haines
Administrator / Office Personnel

Crystallization technology expert Technobis Crystallization Systems has released the Crystal16 V3, a new industry standard multi-reactor crystallizer for medium throughput solubility determination.

With integrated transmissivity technology included in the Crystal16 V3, users can now perform fully controlled and scaled up crystallization studies from hit identification to lead optimization. Users can combine the CrystalBreeder, Crystal16, and Crystalline PV/RR in a flexible configuration to optimize solid-state research.

Check out this Crystal16 V3 video to learn more.

Drug discovery with Crystal16 V3

The solubility of any drug candidate plays an important role in the selection of compounds for drug development. However, Technobis customers report that the HPLC method for solubility determination takes up to 112 hours to complete. This includes the time taken to prepare 16 samples, carry out the multi-stage analysis, and complete equilibration to obtain results.

Laboratories are now seeing increased demands to analyze more samples in less time. This is why the new Crystal16 V3 builds on the success of previous models by increasing the efficiency of in situ laboratory equipment and maximizing sample throughput.

New in-line analytical features

Some of the Crystal16 V3’s features include:

  • Integrated air cooling and extended temperature range between -20 and +150 degrees Celsius
  • Chiller cooling also available from -25 to +150 degrees Celsius with all four block reactors in parallel
  • Flexible, intuitive, user-friendly software with integrated research and analysis capabilities
  • Ground-breaking transmissivity technology with increased accuracy and improved particle detection at low and high concentrations
  • Feedback control, automated decision making and simplified nucleation time measurements
  • Overhead and bottom stirring. Top stirring specifically developed to overcome attrition issues, and bottom stirring for your most simple experiments.

Saving time and resources with Crystal16 V3

Upgrading your crystallization workflow to take advantage of automated benchtop analytical equipment will help scientists save time and resources, while promoting productivity elsewhere in the laboratory.

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