Merck Launch New Shear Protectant Polymer for Biopharmaceutical Manufacture

25 Apr 2017
Lois Manton-O'Byrne
Executive Editor

The Poloxamer 188 EMPROVE® EXPERT polymer from Merck Millipore is a surface-active nonionic polymer used in cell culture media as a shear protectant and has become a standard component to cell culture media for production processes. The new polymer increases robustness of mammalian cells to shear from sparging, resulting in increased viability of cells in the bioreactor.

For biopharmaceutical manufacturers, Merck's Poloxamer 188 EMPROVE® EXPERT polymer helps to ensure lot-to-lot consistency and reliable performance. The product has been cell culture tested, optimized and comes with EMPROVE® EXPERT polymer dossiers to help manufacturers meet regulatory requirements for risk assessment.

Key benefits of Poloxamer 188 EMPROVE® EXPERT cell culture:

  • Superior performance when compared to different suppliers, batches and quality grades.
  • Lot-to-lot consistency.
  • Shear protection assay as release criteria.
  • Complete GMP documentation with EMPROVE® dossiers.

The Poloxamer 188 EMPROVE® EXPERT product builds on Merck's robust portfolio of cell culture products.

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