New Crossflow Filtration System for Ultra, Micro and Diafiltration Applications

The new SARTOFLOW® Alpha plus SU from Sartorius combines high crossflow filtration performance and single-use technology. The easy-to-use system is optimized for ultrafiltration, microfiltration and diafiltration applications used in many downstream processes like purification of vaccines, monoclonal antibodies or recombinant proteins.

SARTOFLOW® Alpha plus SU has been developed for use in cGMP environments for process development, clinical trials and for small-scale commercial manufacturing. The system is ideal for contract manufacturers, research and development and applications with multiproduct throughput.

All product wetted parts of SARTOFLOW® Alpha plus SU are supplied sterile and made from single-use components, making them all ready to use. The system is equipped with a capsulated gamma sterilized bag loop which contains the crossflow cartridge unit, pump tubing, pressure domes, flow meters, valves, bags and tubing. The compact design allows even small volumes to be purified under aseptic conditions on a laboratory benchtop.

“The SARTOFLOW Alpha plus SU combines pre-sterilized single-use technology with process control for crossflow applications. Innovative process solutions from cassette manufacturing, system engineering and development of single-use technologies characterize this product and position Sartorius Stedim Biotech as a total solution provider,” says Dr. Marc Jenke, product manager for Crossflow Systems at Sartorius Stedim Biotech.

SARTOFLOW® Alpha plus SU and its touch screen are splash-proof and can withstand continuous use in both laboratory and production conditions. To make handling more convenient, the control unit and filtration module are separate components.