New Gene Cloning Tool Is a Safer, More Sensitive Option

A new, ready-to-use, safe, sensitive and more flexible alternative to ethidium bromide and other DNA stains has been introduced by electrophoresis specialists CLEAVER SCIENTIFIC (CSL). RunSafe™ is a significant new tool for gene cloning applications which enables scientists to see their samples separate in real time.

RunSafe™ is a non-mutagenic fluorescent reagent that produces instant visualization of DNA bands upon Blue Light or UV illumination of gels. It is easy to use. Simply mix, load and run and it acts as both a loading dye and a DNA stain combined for added speed and convenience for optimum economy and low environmental impact. No expensive waste management is required and it complies with Clean Water Act standards.

Supplied in Cleaver Scientific’s 6x DNA loading buffer, RunSafe™ can be used to prepare DNA markers and samples for loading on agarose or polyacrylamide gels. It is a highly sensitive stain available for detecting double-stranded DNA (dsDNA). It contains three tracking dyes (Bromophenol Blue, Xylene Cyanol FF and Orange G) for visual tracking of DNA migration during electrophoresis.