New Innovations and Research Collaborations in the Cloud Drive the Era of Precision Medicine

Thermo Fisher Scientific, the world leader in serving science, today unveiled new innovations for research aimed at addressing the growing need for early detection, better prognosis, and more effective cancer treatments in the future. These new products were featured at the American Association for Cancer Research (AACR) 2015 Annual Meeting. “Genetic sciences continue to propel cancer research forward, enabling breakthroughs in the lab that translate into future clinical applications,” said Chris Linthwaite, president, Genetic Sciences for Thermo Fisher Scientific. “As research in targeted sequencing and the use of liquid biopsies is becoming more prevalent, and the need for real-time, cloud-based collaboration grows, the scale and depth of Thermo Fisher’s growing cancer research portfolio uniquely suits us to support our customers in the collective pursuit of life without cancer.”

Featured New Products:

• Designed for translational and clinical research laboratories, the Oncomine Focus Assay is a multi-biomarker next-generation sequencing (NGS) panel that includes 52 solid tumor genes that are associated with current oncology drugs and published evidence. The assay allows concurrent analysis of DNA and RNA, enabling sequencing of 35 hotspot genes, 19 genes associated with copy number gain and 23 fusion genes, all in a single workflow using the Ion PGM System.

• In cooperation with the Amazon Web Services (AWS), the new Applied Biosystems

QuantStudio 3 and QuantStudio 5 Real-Time PCR systems are the first qPCR instruments to enable connecting researchers through the secure Thermo Fisher Cloud computing platform, marking a new era in data sharing and global research collaboration. The QuantStudio 3 and 5 systems are designed to allow researchers to learn, analyze, share, collaborate, and obtain support within a single platform.

• The new TaqMan gene expression assays use real-time PCR to detect fusion transcripts. As a complementary solution to NGS panels, the TaqMan assays are designed to serve as an orthogonal validation method, providing a cost-effective and simpler alternative to fluorescence in situ hybridization (FISH).

• Designed for research labs and small biotech firms looking to simplify DNA, RNA and protein purification processes, the Thermo Scientific KingFisher Duo Prime nucleic acid and protein purification system builds upon the utility of the existing KingFisher Duo system, which helps to improve reproducibility and deliver high quality samples in less time when compared to manual processes and spin-column methods. The KingFisher Duo Prime system offers new features to enhance functionality, including a UV lamp designed for easy decontamination and a barcode reader for seamless traceability.

• The automated Cynvenio LiquidBiopsy Instrument is designed to extract and isolate circulating

tumor cells (CTCs) efficiently from a standard blood draw in preparation for both high content imaging and genomic analysis. The addition of Cynvenio’s rare cell enrichment technology complements the Ion PGM workflow to provide a comprehensive sample-to-genomic data research solution for analysis of CTCs, cell-free DNA (cfDNA) and normal DNA in less than 48 hours.