New Nano LC System and Columns for Proteomics Research Launched at HUPO 2015

Designed and preconfigured for straightforward, state-of-the-art separations

28 Sept 2015
Lois Manton-O'Byrne
Executive Editor

Proteomics laboratories can benefit from a new nano LC system with dedicated columns as front-end for liquid chromatography mass spectrometry (LC-MS). The new Thermo Scientific EASY-nLC 1200 system with a pressure capacity of 1200 bar is designed to provide effortless separation performance and high-throughput capacity.

The Thermo Scientific EASY-nLC 1200 system and the Thermo Scientific Acclaim PepMap nanoLC columns will make their debut at the Human Proteome Organization’s 14th Annual World Congress, Booth 301 at the Vancouver Convention Center, Vancouver, British Columbia.

The EASY-nLC 1200 was designed for robust and reliable operation at 1200 bar. New maintenance-free ceramic valves decrease system downtime and tool-free nanoViper connections provide fast and reproducible fluidic connections over the complete flow path. For simplified operation and maintenance, new software features enhance performance and usability. As a result, users at various levels of expertise receive an optimized and fully integrated solution designed to consistently generate high quality data.

“The EASY-nLC 1200’s ability to run at higher pressure enabled us to more rapidly load samples, hence dramatically improving sample throughput,” said Thomas Kislinger, Associate Professor at the Princess Margaret Cancer Center, University of Toronto.

The new Acclaim PepMap nanoLC columns are designed to handle the 1200 bar pressure capability of the EASY-nLC 1200. In particular, the new 75 cm format provides high peak capacity intended to increase sensitivity and resolution. This capability increases the number of protein identifications for improved proteome analysis which delivers excellent confidence in LC-MS results.

“In combination with our leading mass spectrometry technologies, the EASY-nLC 1200 pushes the boundaries in proteomics without compromising robustness,” said Remco Swart, director of LC-MS technologies at Thermo Fisher Scientific. “This newest addition to our nano LC-MS solutions marks an important milestone that brings proteomic laboratories to new levels of biological information.”

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