New Ultra-High Speed LCMS System for Multiplex Analysis Doubles Sample Throughput

Shimadzu Scientific Instruments has released the Nexera MX ultra-high speed LCMS system for multiplex analysis.

Equipped with Nexera MX Dual Stream Technology (MX-DST), the system can process up to twice the number of samples as conventional LCMS systems in the same amount of time. By enabling continuous data acquisition, the Nexera MX system significantly improves analytical throughput, enabling laboratories to operate more efficiently and profitably.

The Nexera MX-DST provides continuous data analysis by incorporating a special flow line structure and instrument control system. The unique technology performs overlap control of sample injection by using two analysis streams alternately. When one stream completes data acquisition, the other stream begins data acquisition immediately. Shimadzu’s high-capacity ultra-fast SIL-30ACMP autosampler enables the Nexera MX’s overlap injections, allowing an impressive 20-second analysis cycle while achieving ultra-low carryover.

In one comparative study of four biomarker compounds, the Nexera MX completed analysis in only 38 seconds, while a conventional HPLC required one minute and 22 seconds.

To simplify user operations and data processing, the Nexera MX system uses custom MX Solution software, as well as Shimadzu’s LabSolutions Insight. The intuitive MX Solution software allows users to begin analysis in just three clicks, while LabSolutions Insight uses special flagging functions to sort and analyze large amounts of data quickly and effectively.