NucleoSpin Plasma XS – Highly sensitive purification of circulating DNA from Plasma

NucleoSpin Plasma XS enables the rapid purification of circulating DNA from plasma. Increased amounts of circulating DNA in plasma have been found in a variety of disorders including cancer, autoimmune diseases, infections, certain fetal diseases, trauma, stroke, and others.

Circulating DNA is known to be highly fragmented and low in concentration which creates difficulties in its purification. NucleoSpin Plasma XS is designed for the isolation of fragmented DNA from human EDTA blood plasma in a range of approximately 50 bp – 1000 bp.

The kit comprises optimized buffer chemistry and a membrane composition especially designed for high recovery rates of fragmented DNA. NucleoSpin Plasma XS allows elution in only 5 μl, resulting in highly concentrated DNA, ready to use in downstream applications like real-time PCR.