Phenomenex Lux™ 10-Micron Chiral Media Now Available in Bulk for Preparative Chromatography

Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, announces the extension of its successful Lux chiral media line to meet the needs of preparative chromatography applications. Lux Cellulose-1 and -2, unique and complementary chiral stationary phases, are now available in 10-micron particle size for batch preparative chromatography.

Lux Cellulose-1 is one of the most successful chiral stationary phases on the market today. The two cellulose-based phases add to a dependable, high-resolution screening set with a wide range of selectivity.

The new 10-micron particles are available both in Axia™-packed preparative columns, and in bulk, enabling customers to pack their own columns for the most cost-effective purification methods. Lux chiral phases Cellulose-1, -2, -3 and -4 are already offered in 20-micron bulk media for use in batch preparative and simulated moving bed chromatography.

Packing columns with new 10-micron particles delivers increased efficiencies by enabling the use of shorter columns without compromising results. This saves time and reduces solvent consumption.

Lux Cellulose phases benefit from Phenomenex’s unique manufacturing process and silica coating technology. Lux Cellulose-1 uses cellulose tris (3, 5-dimethylphenylcarbamate) as the chiral selector. Lux Cellulose-2 provides a second chiral selector, cellulose tris (3-chloro-4-methylphenylcarbamate), providing a unique chlorinated stationary phase with complementary selectivity to Lux Cellulose-1.

“The demand for chiral preparative separations continues to grow in pharmaceutical research and development, as well as in toxicology studies,” explains Marc Jacob, Ph.D., product manager for Phenomenex. “Our Lux media have been very successful in resolving and identifying enantiomers and we are pleased to expand our offering to meet the needs of preparative chromatography applications.”