Proteomics on NGS: The launch of Olink Explore 1536 promises to be a game changer

Olink Proteomics have announced the launch of Olink® Explore 1536

7 Jun 2020
Sophie Ball
Publishing / Media

Olink Proteomics has announced the launch of Olink® Explore 1536, combining the company's unique proximity extension assay (PEA) high-multiplex immunoassay technology with next-generation sequencing (NGS) readout on the Illumina® NovaSeq platform.

Olink Explore 1536 has several groundbreaking features that promise to overcome significant limitations in other proteomic technologies, including remarkably increased performance in terms of multiplexing and throughput. They have achieved these dramatic improvements while maintaining the same robust, transparent and thorough validation of each assay as previously, generating reproducible and precise data that can be trusted.

"I am extremely proud of the Olink team that has been able to take this technology leap and apply NGS as our readout platform. A lot of efforts have been made to respond to a rapidly growing unmet need; drastically increase multiplexing, throughput, drive cost down and leveraging a large installed base to increase access. It is also important that we will rapidly expand our strictly validated protein biomarker library, now in excess of 1500, next year beyond 3000 and reaching 4500 in 2022. This new platform marks a pivotal moment in the field, taking discovery in proteomics to unparalleled levels and supporting our vision to enable the understanding of real-time human biology in a liquid biopsy", says Jon Heimer, CEO, Olink Proteomics.

"I think that Olink will be an important addition to the tools we have for biomarker discovery in plasma, CSF, and other biofluids due to the speed and very small sample amounts required for analysis", says Professor Steven Carr, Senior Director of Proteomics at the Broad Institute.

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