QIAGEN expands next-generation sequencing portfolio with QIAseq Normalizer Kits

Accelerating DNA library pooling for high-quality next-generation sequencing results

9 Jul 2023
James Li
Blood Banking Scientist

QIAGEN has announced the launch of the QIAseq Normalizer Kits that give researchers a fast, convenient and cost-effective method to pool different DNA libraries for best-quality results from next-generation sequencing (NGS) runs.

The QIAseq Normalizer Kit speeds up equalizing DNA concentrations across NGS libraries – so-called normalization – to 30 minutes from several hours by ending the need for quantifying DNA libraries using time-intensive and expensive procedures. It is high-throughput with an optimized protocol for parallel normalization of 96 samples, automation-friendly, and works without hazardous chemicals.

“The QIAseq Normalizer’s big strength is its ability to reliably normalize all library types across a wide range of concentrations quickly and cheaply,” said Dr. Thomas Schweins, Senior Vice President and Head of QIAGEN’s Life Sciences Business Area. “Library pooling is the key to cost-effective, high-yield multiplexed sequencing – and QIAGEN’s normalization kit is crucial for ensuring researchers get consistent and high-quality sequencing data by minimizing any uneven representation of libraries.”

Researchers can use the QIAseq Normalizer Kits with QIAGEN’s existing QIAseq library prep solutions to streamline NGS workflows – or with a range of DNA- and RNA-library prep workflows from other providers for Illumina sequencing platforms. The Kits will enable users to safely store normalized double-stranded DNA (dsDNA) libraries at –20°C for longer-term storage.

QIAGEN’s QIAseq kits have processed over four million NGS samples, enabling biomarker research, gene expression studies, viral epidemiology, and disease surveillance. From DNA and RNA sequencing to multimodal sequencing and epigenomics, the comprehensive range of QIAseq kits delivers reliable data on any sequencing instruments.

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