Quantitative bioanalysis of oligonucleotides using a 6495D triple quadrupole LC/MS system combined with an automated SPE workstation

Discover the power of a high-throughput, automated workflow combining the Agilent 6495D triple quadrupole LC/MS system with Bravo-based solid-phase extraction (SPE). Designed for researchers and bioanalytical labs, it demonstrates how to achieve ultra-sensitive, reproducible quantification of therapeutic oligonucleotides in complex biological matrices, ideal for pharmacokinetic and toxicology studies.