Ready-to-Use Disposable 96-Sample Equilibrium Dialysis Plates

9 May 2011
bridget bridget
Laboratory Director

Harvard Apparatus offers patented 96-Well DispoEquilibrium DIALYZERS™ that provide a simple and reliable method for simultaneously analyzing up to 96 samples on disposable dialysis plates.

Only available from Harvard Apparatus, these unique, ready-to-use, equilibrium dialysis plates are convenient and cost effective tools for ligand binding experiments including serum protein binding, protein-drug binding, protein-protein binding and protein-DNA binding assays.

Equilibrium Dialysis is recognized as the Gold Standard in molecular binding studies as it allows for the direct assay of molecular interactions at near physiological conditions with minimal effects on equilibrium parameters.

Equilibrium Dialysis has also shown itself to be a valuable technique for sample preparation before candidate-analysis by mass spectrometry. Studies have shown enhanced target identification when equilibrium dialysis is used.

Each test-well in the plate consists of two chambers separated by a regenerated cellulose membrane with a molecular weight cut off of either 5,000 or 10,000 Daltons. Each chamber holds up to 300µl of sample or buffer.

Decrease dialysis time by using a plate rotator which is available from Harvard Apparatus in a 1, 2 or 8 plate formats. The 96–well plate was designed with a SBS footprint and well spacing to meet automation needs.

Other equilibrium dialysis products from Harvard Apparatus include the single-sample DispoEquilibrium dialyzer for volumes up to 100µl, the re-usable PTFE Fast Micro-Equilibrium dialyzer for samples 25µl to 1500µl or the Multi-Equilibrium Dialysis System for up to 20 samples with volumes 200µl to 5ml.

For more information please go to the company article page.

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