Redefining multi-kilogram synthesis of small molecules and polymers…

A Lara™ Controlled Laboratory Reactor (CLR) from Radleys has enabled the Organic Materials Innovation Centre (OMIC) (Manchester, UK) to more accurately control process variables enabling safe, precise and reliable multi-kilogram synthesis of small molecules and polymers.

OMIC is a DTI supported University Innovation Centre (UIC) established in 2004 for the speciality organic materials and polymer industries. It is an independently-managed partnership between industry and academia to facilitate knowledge transfer from the universities to industry to help businesses to innovate and grow. Using its wide range of expertise and facilities OMIC works with companies to help them develop strategies for the synthesis of novel organic molecules and polymers.

Traditionally OMIC had employed a range of large glass reaction systems developed with parts sourced from several suppliers for multi-kilogram syntheses. However operating these systems had drawbacks both in terms of accurate control of process variables (heating, cooling, addition profiles) and difficulty in exchanging vessels, which was particularly labour-intensive and time consuming. Data logging required the use of external portable equipment that was cumbersome and did not fully integrate all parameters.

Radleys was chosen to upgrade OMIC's larger scale synthetic capabilities as the elegant integrated hardware / software solution provided by the Lara CLR delivered the required operational versatility, ease-of-use, precise control of process variables and accurate reaction data logging. Professor Stephen Yeates (Co-Director of OMIC) commented 'we have been delighted with the knowledgeable support provided by Radleys that enabled us to rapidly implement the Lara CLR system thereby providing an improved multi-kilogram synthesis service for our customers'.

Looking to the future OMIC are now investigating how the Lara CLR can further assist them in developing new and improved synthetic approaches in projects ranging from classical organic to novel polymer chemistries.

For additional information on how the Lara CLR can help improve your multi-kilogram organic material syntheses please contact Radleys.