Scale Biosciences and Revvity’s BioLegend launch high parameter protein profiling of single cells
The TotalSeq Phenocyte solution supports robust study of cellular heterogeneity and rare cell types in complex samples at a single cell level
18 Dec 2024
Scale Biosciences and Revvity’s BioLegend® business have announced the availability of a new, first-of-its-kind TotalSeq™Phenocyte™ single-cell protein profiling solution that supports customers by more easily identifying and characterizing rare cell subtypes, which ultimately powers immunology and oncology research.
The solution is enabled by the proprietary combination of Scale Biosciences’ Quantum Barcoding technology platform and BioLegend’s TotalSeq™ antibody conjugates.
While technologies like mass cytometry and high-parameter flow cytometry enable protein analysis at the single cell level, these approaches require complex panel optimization and sophisticated instrumentation that limit their accessibility and scalability across multiple samples.
The new offering builds upon BioLegend’s well validated TotalSeq-A™ antibody panels and Scale Bio’s Quantum Barcoding technology workflow. The combined offering can be used to power biomarker discovery and the identification of rare cells within a heterogeneous population without complex panel design, complicated workflows, or dedicated instrumentation.
“By leveraging TotalSeq antibodies and a single-cell genomics-based workflow, this product supports the identification of low frequency events within a cell population. This allows for the study of many more markers than could be observed in a single experiment using other cell analysis technologies to study cell populations,” said Craig Monell, senior vice president, reagents, Revvity.
“Scale Bio is focused on leveraging the power of our new Quantum Barcoding technology to enable researchers to dramatically scale up their research by being able to explore more cells, more samples, across more modalities, with simple workflows and an accessible price point,” said Giovanna Prout, president and CEO of Scale Bio.
For research use only. Not for use in diagnostic procedures.
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