STEMCELL Technologies and Axion BioSystems partner to streamline culture and analysis of excitable cells

Through this partnership, Axion and STEMCELL will enable scientists to examine the complex interactions between electrical cells in vitro, driving mechanistic disease research and propelling therapeutic development in neural and cardiac fields

23 Sept 2024

Axion BioSystems and STEMCELL Technologies have announced a strategic partnership that will enable STEMCELL to sell Axion’s Maestro Pro™ and Maestro Edge™ multielectrode array (MEA) systems within North America and Europe. The Maestro MEA systems will also continue to be available for purchase worldwide directly from Axion BioSystems.

Conventional electrophysiology methods, such as patch clamp, have been instrumental in establishing our understanding of cell processes and disease mechanisms in electrically active cells. However, they can be tedious and complex, requiring extensive training to collect recordings from single cells at low throughput.

Maestro MEA technology makes quality electrophysiological data accessible, reducing the technical barriers and throughput limitations by measuring from a grid of microelectrodes embedded in multiwell plates. Dynamic activity patterns can be measured noninvasively across an entire population of cells, enabling researchers to record real-time responses to experimental stimuli and assess changes in cell network function over time.

Versatile and user-friendly, the Maestro Pro and Edge systems make it easy to adopt advanced MEA technology, empowering researchers to address impactful experimental questions with functional data while accelerating the pace of their research.

STEMCELL offers a complete workflow of high-quality cells, media, reagents, and supplies to support functionally active cultures. By using Maestro MEA systems in combination with reliable, ethically sourced iPSCs or differentiated cells, BrainPhys™ Neuronal Medium, and STEMdiff™ kits (e.g., neural or cardiomyocyte), users can quickly achieve highly active cultures with simple, straightforward protocols, ensuring reproducible experimental results.

The complete Maestro MEA platform, including neural and cardiac analysis modules, consumables, and instrument service plans, will soon be available through STEMCELL.

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