The Communauté Européene (CE) Marking Granted for Millipore’s Amicon® Ultra-15 Centrifugal Filter

Millipore announced today that the European Union’s Council of Ministers has granted a CE mark to the company’s Amicon Ultra-15 centrifugal filter device (10K molecular weight cut-off). This indicates that the product meets all essential requirements set forth in the In-vitro Diagnostics Directive.

The measurement of specific proteins is important for the diagnosis and management of disease states. In some cases, the proteins of interest (such as macromolecules found in human specimens such as serum, urine, spinal fluid, and other biological fluids) are present in low abundance and require concentration prior to clinical laboratory analysis. Millipore’s Amicon Ultra-15 centrifugal filter unit provides ultra-fast, high recovery purification and concentration of these proteins. This can be valuable prognostic indicators of specific abnormalities, such as tumor cells.

Sample volumes up to 15 mL can be concentrated in as few as 10 to 15 minutes with negligible loss of sample. The device’s Ultracel™ regenerated cellulose membrane minimizes adsorption of the macromolecules and provides high recovery of fully functional proteins (typically >90%).

Amicon Ultra-15 centrifugal filters are compatible with most rotor types and allow for direct pipettor acess, which eliminates the need for an extra processing step. The device is available in packs of 8, 24, and 96 filter units, which come assembled with centrifuge tubes and caps. Millipore also offers the CE-marked Amicon Ultra-4 centrifugal filter device for sample volumes up to 4 mL.

Millipore’s Bioscience division delivers complete solutions and services for pharmaceutical, academic, life science, clinical and government research laboratories. With more than 50 years of experience, Millipore manufactures and markets several thousands of products that accelerate drug screening and improve sample preparation. For more information, please contact Millipore Tech Service at 1-800-MILLIPORE, 781-533-6000 or visit www.millipore.com/amicon.