NewsLife Sciences
The SensiQ Family of SPR Systems – New Surface Chemistries
5 Jun 2008ICx Technologies recently introduced a range of new chemistries to complement the existing planar COOH chemistries and gold only surfaces. These include the following:
- Biotin capture – This is a neutravidin-based planar surface designed to work with biotinylated proteins and oligos.
- Avidin capture – Another planar surface that takes advantage of the high affinity of the biotin-avidin complex, this surface utilizes biotin on the surface to capture avidin conjugated proteins.
- His-Tag Capture – This surface utilizes the Ni-NTA complex to capture His-tagged proteins for subsequent binding to biomolecules.
- Hydrophobic – This is especially well-suited for the immobilization of vesicles or membranes in the study of receptor protein binding interactions.
- High Capacity – Various three dimensional matrices are available for those studies that require surfaces with higher immobilization capacities for applications such as protein-small molecule interactions.
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