Thermo Fisher Scientific Launches New Easy-to-Use LCQ Fleet Ion Trap Mass Spectrometer

Thermo Fisher Scientific Inc., the world leader in serving science, announces the launch of the Thermo Scientific LCQ Fleet™, the latest addition to the company’s industry-leading portfolio of LCQ ion trap mass spectrometers.

The LCQ Fleet LC-MS system provides cost-effective, rapid and confident sample analysis for routine analysis in the general analytical lab as well as toxicological screening, natural products characterization and peptide identification applications. This reliable and easy-to-use ion trap mass spectrometer, from the inventors of the technology, provides maximum information in minimum time with exceptionally low levels of sample consumption. The combination of the Thermo Scientific Accela™ High Speed LC and the LCQ Fleet will be showcased at the downtown Marriott Ballroom 5, daily from 7:00 - 10:00 PM during the 55th Annual ASMS Conference on Mass Spectrometry.

In clinical and forensic toxicology, LC-MS is increasingly being used for the detection and identification of xenobiotics in applications such as General Unknown Screening (GUS) and Systematic Toxicological Analysis (STA). Designed to perform with high sensitivity and specificity, the new LCQ Fleet is capable of producing more accurate results at lower detection levels with high throughput, especially when used in combination with the Accela high speed LC system. Intelligent Data Dependent™ acquisition of the LCQ Fleet enables rapid compound screening for maximum structural information.

When analyzing natural products, traditional approaches have proven to be particularly time-consuming. Featuring a fast cycle time and excellent MSn spectral quality, the LCQ Fleet enables rapid identification and characterization of known and unknown natural products without the need for a lengthy pre-purification process. Furthermore, the Ion Max™ source delivers outstanding robustness for the most demanding analytical applications. The high quality MSⁿ data can be searched against the built-in or user-defined libraries embedded in the Mass Frontier™ software for compound identification and data reporting.

The LCQ Fleet also enables routine peptide identification with high correlation scores for confident sequence identification. The fast scanning capability of the instrument resolves co-eluting peptides often present in complex protein digests. The LCQ Fleet operates on the flexible, Windows^®-based Thermo Scientific Xcalibur™ software platform, which provides automated LC-MS/MS instrument control as well as quick and efficient data acquisition, processing and results delivery. The robust LCQ Fleet is capable of generating dependable results for routine compound identification in complex matrices.

For more information about the new Thermo Scientific LCQ Fleet ion trap mass spectrometer, please visit booth #54 at ASMS, Indiana, June 3-7. The company will also be presenting a poster “Profiling and Characterization of Polyphenol Polymers from Cinnamon Using Ion Trap Mass Spectrometer”.