Growing together in cell analysis Agilent | SelectScience

Growing together in cell analysis​

Cell analysis tools provide a means by which to better understand the molecular mechanisms that define cell function and behavior. Placed in the context of disease and therapeutics, cell analysis forms a vital component of the drug discovery workflow. Accurately characterizing how cellular ecosystems and cell-cell interactions drive physiological processes has the potential to direct the development of future therapeutics.​

Having the appropriate solutions for your cell analysis workflow is vital for the success and reliability of your discoveries. Agilent Technologies provides unique value to science in the cell analysis arena because of the breadth of its portfolio and expertise of its workforce. The advanced cell analysis instruments from Agilent Technologies allow deeper insights into characterizing cell function and behavior. ​​

Jump to the area of research most applicable to you to find a selection of useful resources and see how the Agilent cell analysis portfolio can provide a complete solution to cell analysis in your lab.​

Oncology & immuno-oncology

Immuno-oncology research is changing the landscape of cancer treatment by harnessing the immune system to attack cancer cells, offering promising new approaches to cancer therapy.

Explore the Agilent immuno-oncology research tools for assessing real-time cell function, phenotype, and fate.

Cell metabolism, migration & invasion

Get ahead by knowing the metabolic programming
Explore how the Agilent Seahorse XF Pro Analyzer can identify cancer malignancy

Dr. David Ferrick, Associate Vice President for Cell Analysis at Agilent Technologies, discusses how tools have progressed the field of cancer and immunotherapy research. Watch this 5-minute educational video to learn more about how cellular metabolism and Agilent Seahorse XF technology works, and how real-time quantitative and qualitative measurements provide deeper insights into processes including proliferation, differentiation, cell death, and activation — to advance science and develop therapeutic strategies.

Cell metabolism, migration, and invasion play key roles in cancer progression and drug resistance. Investigating how to target these cellular processes could lead to the development of more effective cancer treatments.

Agilent cell analysis technology enables the measurement of several metabolic parameters and functions using live cells, in real time, enabling researchers to assess energy expenditure, substrate utilization, mitochondrial function, and general cellular homeostasis.

Explore these resources to see how Agilent Seahorse XF technology allows for real-time, label-free analysis of cellular bioenergetics and metabolic pathways.

Seahorse XFe Analyzers by Agilent Technologies
5 stars
“Reliable, sensitive tool for cellular metabolism research!”
Jessica Pierce​
Emory University​

Immunology​

The immune response is a highly regulated process consisting of many cell types, designed to protect the body from microbes, toxins, and tumor formation.

Advanced cell analysis tools are used in immunology to provide insights into the complex interactions between immune cells and other cells in the body, as well as the factors that regulate immune responses.

BioTek Cytation C10 Confocal Imaging Reader by Agilent Technologies​
5 stars
“Dear Santa, I have been a good scientist and now I want my own Cytation 10 for Xmas!”​
Alexander Karabatsiakis
University of Innsbruck
Agilent Seahorse XF live-cell metabolism solution for immunology research

Advanced cell analysis tools are used in immunology to provide insights into the complex interactions between immune cells and other cells in the body, as well as the factors that regulate immune responses.

“Great technology! It changed my life.”​
Zunair Khokhar​
University Of Virginia​

Download these scientific resources and uncover the complexities of the immune system and its impact on health and disease with unique cell analysis research tools from Agilent. These instruments facilitate a deeper understanding of the immune system and its role in health and disease, ultimately leading to the potential development of more effective immunotherapies.

Microbiology & virology

Virology research has broad relevance to human health, from revealing mechanisms of host-pathogen interactions to more applied translational research on immune system response.

​The Agilent cell analysis portfolio of products offers a complete solution for your virology research.

Download the resources to find out how Agilent solutions can provide real-time, label-free monitoring of cell growth, viability, and infection, as well as high-throughput screening of compounds.​

Investigating effects of respiratory syncytial virus infection on host cell mitochondrial function
This application note summarizes how Hu et al. employed the Agilent Seahorse XF Cell Mito Stress Test to show that that RSV drives a staged redistribution of mitochondria in infected cells.
Automated viral plaque assay workflow using the Cytation cell imaging multimode reader
This application note presents an assay that provides an accurate and efficient method for determining plaque counts and calculating viral titers in a range of microplate densities, including 6-, 24-, 48-, and 96-well formats.
vaccine and virology handbook​

Download the vaccine and virology handbook​

Current methods to measure virus and neutralizing antibody titers include plaque assays, plaque reduction neutralization tests (PRNT), or immuno-focus assays. These methods are labor intensive and have inconsistent results due to the variable rate of plaque formation and optimal time points to count plaques for each infection. ​​

With xCELLigence Real Time Cell Analysis instruments, you can track viral cytopathic effects continuously without the use of agar, dye, or fixative over minutes to days. These automated assays greatly reduce workload and provide quantitative kinetics for the entire virus life cycle.​

​Download to learn about a simple and high-throughput workflow to easily evaluate:

  • Viral titers
  • Neutralizing antibodies
  • Anti-viral drugs
  • Virucides
  • Oncolytic viruses
  • Virus quality & fitness

High-throughput screening & drug discovery​

High-throughput screening allows for the rapid and efficient screening of large numbers of compounds, helping to identify potential drug candidates more quickly and efficiently than traditional methods.

Expand your drug discovery and development pipeline with cell-based assays. Download the scientific resources to discover how the Agilent cell analysis portfolio of products delivers a complete solution for drug discovery and development, and toxicity studies.

xCELLigence RTCA CardioECR by Agilent Technologies​
5 stars
“Very easy and convenient to use and allows for very informative readouts in a high throughput fashion!”​
Fabian Zanella de Sa
University of California​
5 stars
"Great and precision results. A key to success for drug discovery.”
​Muhammad Fayyaz
University of Illinois
5 stars
“I have never met a very cheap and highly capable cytometer like NovoCyte.”
Rogers Alphonce
Self-Employed​
Principle of mitochondrial toxicity assessment using Agilent Seahorse XF solution
This white paper outlines the approach and design of the Agilent Seahorse XF Mito Tox assay solution for the detection of mitochondrial toxicity using standardized parameters.
Expression and intracellular translocation of cancer biomarkers in hepatocarcinoma cells
​This application note discusses the development and validation of quantifiable, simple, and fast methods for screening anticancer drug candidates (small molecules) in tumor cell cultures.
The Agilent xCELLigence RTCA CardioECR System
Learn about the xCELLigence RTCA CardioECR system, a dual-mode instrument that includes directed electrical pacing of hiPSC-CMs as well as simultaneous monitoring of hiPSC-CM viability, contraction, and FP in real time.

*Images courtesy of Agilent Technologies®.
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