PlasmidFactory GmbH & Co. KG

PlasmidFactory is a contract manufacturer for plasmid DNA from research scale up to industrial scale for R&D, DNA vaccination, gene therapy, virus production, drug delivery, or tumor therapy. The plasmid DNA is manufactured from Research Grade up to GMP Grade quality without using any animal-derived components. DNA is delivered in unbiased and reproducible quality in guaranteed amounts, requested buffer and aliquots by overnight courier to PlasmidFactory´s customers.

Besides the service production of plasmid DNA, the company offers a gene synthesis and optimization service, In Stock plasmids for reporter gene vectors, mock transfections, pDG vectors for AAV virus production and pEPI vectors with S/MAR.

PlasmidFactory´s R&D. All services are performed in Germany. With two BMBF grants and European research collaborations (FP6) the company is the leading force in gene vector development.

The company has developed the capillary gel electrophoresis (CGE) for quantitative analysis of plasmid DNA topologies. CGE is a useful tool for plasmid quality control, storage and stability assessment.

At present a high efficient Minicircle DNA system was developed to obtain non-viral vectors without antibiotic resistance elements, other selection markers or bacterial (CpG containing) sequences.