Products & ReviewLife Sciences

16,16-Dimethyl Prostaglandin E2

Prostanoid pathway activator; Inhibits 15-hydroxy PGDH

STEMCELL Technologies Inc.

The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our  Product Directory.

Ease of Use
After Sales Service
Value for Money
Write your own review

16,16-dimethyl Prostaglandin E2 (16,16-dimethyl PGE2) is a competitive inhibitor of 15-hydroxy PGDH (North et al.; Ohno et al). 16,16-dimethyl PGE2 acts as an agonist on most prostaglandin E (EP) receptor subtypes (Coleman et al.; Robert et al.) with a Kd for activation of about 1 nM (Coleman et al.). 16,16-dimethyl PGE2 is supplied in methyl acetate solution at 10 mg/mL (26 mM).

MAINTENANCE AND SELF-RENEWAL

  • Increased hematopoietic stem and progenitor cell (HSPC) numbers in zebrafish aorta-gonad-mesonephros (AGM) region and mouse bone marrow (North et al.).
  • Mediates the effects of WNT on zebrafish HSPC self-renewal (Goessling et al.).

Product Overview

Links