Agilent NanoDis System

Agilent TechnologiesAvailable: Worldwide

The NanoDis System provides formulation scientists with accurate release profiles of APIs using conventional dissolution apparatus in an automated, compliant manner. This functionality enables analysts to uncover the best nanoparticle formulation faster and get new drug formulations to market more quickly.  

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The NanoDis System provides formulation scientists with accurate release profiles of APIs using conventional dissolution apparatus in an automated, compliant manner. This functionality enables analysts to uncover the best nanoparticle formulation faster and get new drug formulations to market more quickly.

Easily transition from R&D to QC environments and achieve consistent, reliable dissolution results for nanoparticle-based formulations in an automated process while ensuring cGMP compliance.

Features:

  • Reliable API filtration: Individual samples flow through commercially available hollow-fiber membranes to either the 850-DS for collection (filtered) or back to the dissolution vessel (unfiltered).
  • Regulatory compliant hardware: The NanoDis System incorporates standard dissolution instrumentation (708-DS and 850-DS).
  • Sample flow dynamics: Exclusive dual-pumping sample flow sequence in the closed-loop system maintains surface-area exposure of nanoparticles for consistent dissolution release-rate profiling.
  • Software control: Optimize method parameters and regulate system access using Agilent Dissolution Workstation Software—a proven platform in cGMP-compliant environments.

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